Unlike synthetic chemicals herbal raw material can not be produced in factories. Compared with conventional preparation herbal products present a number of unique problems when quality aspects are considered. These arise because of the nature of the herbal ingredients. Which are complex mixture of constituents, and it is well documented that levels of plant constituents can vary considerably depending on the environmental and genetic factors. Several cases of adverse effects of herbal drugs have been reported in developed countries during the last few years, which are allegedly caused by taking herbal products or traditional medicines. Herbal products may be contaminated with excessive banned pesticides, microbial contaminants, heavy metals and chemical toxins which cause various deformities like congenital paralysis, sensori-neural defects, liver and kidney damage etc.